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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b708a2d1f398280b0a35a90e6ec8ef08b079c08b0134d53f9e5d9edeea230597' 
  AND token = 'TrI2zlJBnmHMFeimCStvqbPUwZoRgiSxN70uesGkF5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}