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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d620937305e5855c8f4c8e5167d0ebabbafb466ac0319a31601e92b4671fbb' 
  AND token = 'yXKRAYBMx15p35qkCf7lvFBmK3qikShJ0cHH5Dz1/Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}