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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9972723a34e40bff4c43e2a150645ea1bbd0c63beb152f3cc511acfc02b0de0' 
  AND token = 'kF03lJRtbUkMPVLTb6Ke+TbhTjAjFCTxlz77IIIFvs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}