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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9d859ac9f842bdde48b3e974083e68e6055359a83b81e1d0999794c580b640c' 
  AND token = 'CU26VimsOBANjafacrbEo+oVszvoEol8dshq75FFvbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}