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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded6ab6baaba97b3cd724f6020b1c4f0915ecaf4581457848355a0735b45b85b' 
  AND token = 'xd4apzZcuWtLwNfSP78x17STc5sl5f2XoDgR7DMxX2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}