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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03b748465dd937f097fb92d4355397342c2aeb565b540389ca6d89b0ba9bf9f' 
  AND token = 'IcsJbknlV4M4BmyTrXdpmdv1T14cymTEIM05LIWSElQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}