SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d469e1db63f4d36bf066fa283b9d2316503a2436caa8689a01ed11b34704bf' 
  AND token = 'hTWsCRXMoeiI/X705a2CFm+0WyQDPClTWq5pplMj/Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}