SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7d9be00176957058d4142327a74ac31a60cfbe2242f6d21eded0077a0aaa9c' 
  AND token = 'eZGatL0MDn4qBG81h9OVUIn3hTG51W9QtSMHu79nHjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}