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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c69e5a2030286e6b5881748b49dfdbbd4ff0708ec43c4ffea4953df408fb20' 
  AND token = 'b1hM+G8LnbZTOgBIZK2Ceko/9zn2sFDsjtwxFO3n5ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}