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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422c287b100760b577bf7716a79d78738905b85eba0be16273fe70d7d7105f9c' 
  AND token = 'iK7OLSasI8uIrEq+3VPur11+ENZ1bLcp4Dvgf1zTcq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}