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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4559a49de1aed6e5e3874ce7219d2c91064b1cf617339320fdf29d4475227109' 
  AND token = 'Hm9lyiBl2R/5a/fMR/Ofm26Pm3+6TMhL7f2qYIGzeF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}