SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657b06a35341389999f0444c13e91507f3fd5a3ad74bbb03335bf9884848f4cb' 
  AND token = 'RIVqerDusOfVuu7PVCMKA5X+eforfdDLuiU4pnnDHZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}