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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1a8113025d32dc83bdd930226a398c647ab4708110d7a52e0f67647c2be7c4' 
  AND token = 'uLbQQ36qHXwkZ+345rIncCH8GSlfRnqem1yo95AzQ30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}