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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d4ea431dd92c8999a5d852660da1febe9db9e362ecf71d8a737c5b0f5ab5a3' 
  AND token = 'ZDE1CB/PdtAM1Alk5LdMtNLktyXfATtjpk6f/eAaHBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}