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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b53f94cc12943c4fab32c511917151fde544927b2fa2970f0f8d1a5ab9198f8' 
  AND token = 'aE//9k8Rba2dUd/PprwWrctEgcMdO+JcrHLdoBy4drs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}