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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846f6f92a7621efbaa276d8cc15f0c80c65627eafbb19124e24dd6ad8f84f485' 
  AND token = 'Jo8GiIRYxANVaYMk/G6sPZyzOB3JtPr7Sd+esYeU2bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}