SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c618ce4350ce37398ea3c8ecb3c930518f6988e722d649b63a45e1db7cfd41' 
  AND token = 'BvFzMjVCM64VVPpJ8cmg1SUCNgBIyt4vNhM2IKC8cIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}