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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7322425ccb6edd2473e74a18790f0b7c4552a9ed498add5cdc9677016f642a00' 
  AND token = 'tuvC0hD9rEYkEkpQ/BJGp0/uvJrip4owufDFGMRrBIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}