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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aac17ef29a8ad17ea00a423e2aaab92a81428740f7abec3591f51bcec3ed23de' 
  AND token = 'GmK3BIJmdWsAc5YM/TTtnUAyOKBMfilipL0KQx7ZjsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}