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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a3035914b48fe8db99edaf2945dcf9dce44b47a83b626076e7e1148d5b7bc81' 
  AND token = 'J+M/oHifSzDkeiYgbyFCqQeAn16FQmQHo0ZwNh38LAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}