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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4b391245c24d5dad7f57c4afb524c5128db650f8fc53a2c80f4293719a15a8' 
  AND token = '4xm+9QkzDEvrs40A4frkf4YT1fmPDW05YaDjMDMdsL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}