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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fc0b8c364d33a9218f504bbfc58b824a870b7060c70372573b52733e45d92c2' 
  AND token = 'I3fs5fwGlgqgCui1epOn9xnQDd2D/ZfZNglx6HBdqtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}