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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48ac1eb6d46e2f0a2cb8ba94c85534f8a93e82ef5dfe8202a85754b8def4999' 
  AND token = 'B0ZTq13XrCCImIzsUROFF/7A6QEGxARTuM9N3AD6WZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}