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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3d80b4af85e213588aa15b377c58a6c22bbd3b2b7fef12df67b8089c8425282' 
  AND token = 'Ff/r5D/1XJuGd00jqiUXzNYcC1DQ/M2CmBpzo+c9p+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}