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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f1859a4853532c48dc2f6c3a825b5d2e685ca634d5852ac5892875844e3c05' 
  AND token = 'RjPs3jRrfcmFSx6qD+mDTny+blv9SVuVDNwHr2dxW1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}