SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f74cf0c3d0ff0100294353935fdca7ba04a2b8ba2c0b54dc17c7bda92d8105' 
  AND token = 'hN1MEw7Xed1xIXRKlqOarBteOkDF7efTDgyW37zZZ8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}