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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef755481771ce2ed4ae3b59d94d4108858ce02d480435ba7d0ee01ce7a050b15' 
  AND token = 'lnui4Aa0/8v3zFv33+OgHpxsZAZB690P8KRkWcWO8JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}