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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4463fa97f3918f6d113779a8dd47aa2f8ab67058394cd746d28e0236361988a3' 
  AND token = 'OKALejm4YCD1GrcAF5+/wc4LixdwjwYfc0uaA/KNe9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}