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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422be45b386ee0431f0ea1b7c8738699e5d574a012c3fbec12a6db63553df669' 
  AND token = 'HY3nSwGjzIl08Z0iy1lzyfS+nbFXrh5XKf02i7nj9x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}