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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f589b0c7cb019f46c8d678b41fc7667b1c762c34dd01b526f4f262fc9d4ea3' 
  AND token = 'iY4rCw3x9aM7cIG2Pb8s+D6jx8GRO1MDa2LTUov6Txw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}