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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bdf7363680b380c15b7bd9573d8a0ed817ef3aa244a9dc1d255b1ebb784c8b9' 
  AND token = '7+ME+yyBMiYBPDl4cGRUVf2gZN3dt7ka4Gf2GRtI9rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}