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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0966cdaf09b1434972a880475b7108002f62b0a77610477f424672d4562125ae' 
  AND token = '/Ci0q/PlFuL1k03bdYxdPAtA9iRWX6EqEH9aq9ewucE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}