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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380aa5b0abbe104cabe162acd1c73e4880d6a6b32cb7a328c22d11217a7b9929' 
  AND token = 'N7lkuiMWXuEeREy45akOw8RmIYg+VDKStqS2oY7z66o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}