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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa504263c743c55f6256c8131aeca2c460f8aa2c2e8da2a7bf53c205c6b75d74' 
  AND token = 'nqupRUVakt1EtDr/25oPD9U+EuyzN/GZsv6dByoi44g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}