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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6dcb8c3fbbdc6486a6ae55d6682f95bda0218818dc978c2d84ae466769ad659' 
  AND token = 'iPE10OQi+SY34JjS1YQq/K+WUd2qPuDZ1UbhzrEhQ5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}