SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75cfad5913c7f4117eb8403a1ae1bcc19818aa9874a64a44a4c032bb2d368bd8' 
  AND token = 'UlQsz+qk4Zz9TvCzZW9jHOpKSjbPF9tpK21UD9dykuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}