SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1673cfd994a58aefedebdd8d5eb97a8436a7d5253b3397c22dcdac98f4b42016' 
  AND token = 'OE9EYXZrpr4NyBsfYljg2coaStqDE0dleFT355b8yKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}