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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60051c01fc78ffeb30d39d17a95d9b7dbe92f8be970ef7f90f8abd954b01a32d' 
  AND token = 'uyRvtUFBOagQ1/RaI5xMR+rDFgAvCML2BBBJ9pOjDtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}