SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4313cb3500b5c1103f5a573388b2a2548dc3ef5f3d8cc596e1e517a8154cb43' 
  AND token = '+bV3j8CGfo30M1ymmyb7QS4wE1HOw9gxc6tPHun+SaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}