SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5713d3b40714b2af80e82f81a8a1940a9e610093bc1f7e27808f9076e2aa6a4e' 
  AND token = 'E9VgBiVBYRTKwPLUJ53yDkDxs//h40Iuw0QF/WO6v1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}