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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f45b3e530be9c2b16a9313468b696d1281b86e6e0a6b9b54b53b2aa35ebd5f1' 
  AND token = 'EkRJBeACASTTa5hW4efHHFYSsWaxSZ8sgAfywpGXoHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}