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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb2e7de676213461e260017f8bb89d7cd914143aa33ceeac9deca6d9d9c6e36' 
  AND token = '+28dWLle4rF+ay4UaJO4PYTBEXU2WDjhQQPrFwOINQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}