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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5341da5237f59a6337729d1dd007ea1dad18499f1b7a63a0f62c0319513c0754' 
  AND token = 'RGpESCFHOAxo8/IT6p65FuiSLet0yKUuC8VchDfmWfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}