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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1973462cbf1fd50a42fd7446917d1a526a38c300af6b6930a2b0992ac5aaed3c' 
  AND token = 'GdXk7EEG8i9AAIW74t+RazEqXl5RzFt0VUlXpAv1R5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}