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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cde49dec151fb8cabcf42d984fd28fb93076bb274ab75b94cba68a83ee2dc18' 
  AND token = 'mnLIU+x3GdGawuy8VSLuQCIqMBwbtdGeAtzaYXU+1UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}