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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1ea32639ca54ea4ce14e082ed3cecbef2d4e2413db907bd94393a57db6be5c' 
  AND token = 'A7RU8hQ0Vkfpj6opxKSTVqpGmtvJ8yDlumyH/4n69Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}