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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b64c50297aef0f9c49b5cf1bcfed9160f3ab622130adb3a9144b38e8c001a01' 
  AND token = 'mv5peXU57+DG0smcYc92GeNj9EqydUcwYDdb/z+D6bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}