SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc788cf6f6281a8b0e25c05c239ca01fe1c82fcc804a2814f65b476095f294b' 
  AND token = '8UGYIx0u4LPANfc3y0EFHe585QXU9UkiDr0RRvjQBjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}