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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89eafe70271f4a923a2c59998c1ed3e9c5ae49fa0284d755274b94f3e8c11a6' 
  AND token = 'Dk2dm+B1fd0JS1vOCENPlku79PqYErGYcjEfP45CP28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}