SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0806fb7b816f00a6ac63f61df541176f3e0c4cbed5e95183918fb54adaa06994' 
  AND token = '22zzPr7Hc2v9vvfLj/QPeCgijKqRHfKgoRene2orhsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}